POSTAMPUTATION PAIN: EPIDEMIOLOGY, MECHANISMS, AND TREATMENT

Postamputation pain: epidemiology, mechanisms, and treatment

Eugene Hsu,1 Steven P Cohen21Johns Hopkins School of Medicine, Baltimore, MD, USA; 2Johns Hopkins School of Medicine and Uniformed Services, University of the Health Sciences, Bethesda, MD, USAAbstract: Postamputation pain (PAP) is highly prevalent after limb amputation but remains an extremely challenging pain condition to treat.A large A Literatu

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Back to the drawing board-relearn the clinical skills: A root cause analysis of a missed case of bilateral vocal cord paralysis

Bilateral vocal cord paralysis being misdiagnosed Človek verzus stroj: „strojové učenie“ a jeho vplyv na modernú spoločnosť (Human vs. Machine: „Machine Learning“ and its Impact on Modern Society) as bronchial asthma has been reported in the literature on several occasions.Diagnosing this condition needs precise clinical acumen which

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The improved efficacy of Sifuvirtide compared with enfuvirtide might be related to its selectivity for the rigid biomembrane, as determined through surface plasmon resonance.

Most mechanistic studies on human immunodeficiency virus (HIV) peptide fusion inhibitors have focused on the interactions between fusion inhibitors and viral envelope proteins.However, the interactions of fusion inhibitors with viral membranes are also essential for the efficacy of these drugs.Here, we utilized surface plasmon resonance (SPR) techn

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Cross-talk of inflammation and cellular senescence: a new insight into the occurrence and progression of osteoarthritis

Abstract Osteoarthritis (OA) poses a significant challenge in orthopedics.Inflammatory pathways are regarded as central mechanisms in the onset and progression of OA.Growing evidence suggests that senescence acts as a mediator in inflammation-induced OA.Given the lack of effective treatments for OA, there is an urgent need for a clearer understandi

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